First 3-Person-Baby Born Using New Method

Scientists say the first three-person baby has been born. The five-month-old boy was treated by a US medical team in Mexico, where the procedure is legal.

The baby was created through a controversial technique that combines DNA from three different people.The technique allows parents with genetic defects to have healthy babies. The boy's Jordanian mother carries Leigh syndrome, a fatal neurological disorder, which is characterized by progressive loss of mental and physical abilities.The condition is responsible for the deaths of the mother's first two children.The "three-parent" technique developed by Dr. John Zhang of New Hope Fertility Clinic in New York, removes the DNA from one of the mother's eggs and inserts it into a donor's egg.

The egg which holds DNA from both the mother and donor is then fertilized with the father's sperm. Zhang created five embryos this way -- only one developed normally. The embryo was implanted in the mother. While some are touting this as a success, those against the procedure say it raises ethical questions, and doctors shouldn't play God.


How To Choose An Orthodontist? Dr. Matthew Freedman In Naples, Florida Explains

Many parents will face the prospect of choosing an orthodontist for their children. Getting the right dentist is especially important for a process that will go on over a period of time. In this report, Dr. Matthew Freedman, an experienced orthodontist, explains what parents should think about and look for when making the big decision.

The obvious first consideration is proximity. Parents need to think about where they live, where they work, and what their schedules are like, including their children’s school schedules. Monthly visits to the dentist will require that everything fits together.

Dr. Matthew Freedman

Dr. Matthew Freedman

Dr. Freedman suggests that parents find an orthodontist who can deal directly with their dental insurance company. “That will be an important piece of the puzzle” for families with insurance. Dr. Freedman says that his office handles the insurance for his patients, submitting the claim and dealing with insurers to get claims paid. Patients then pay only the amount not covered by insurance and are spared a lot of hassle.

Parents should try to find an office they like, one that is pleasant to visit and that makes them and their children feel good. Monthly visits to the orthodontist should be a good experience. Parents should look for a dental office they will want to come back to.

Dr. Freedman points out that there are things parents should avoid. First off, watch out for “anything that sounds out of the ordinary.” Most parents know how their children’s teeth look (and it’s easy to take a look). Parents usually have a sense of how bad their children’s teeth are and how much work might be involved. Parents should be wary of strange dental appliances or a treatment plan that doesn’t make sense. Parents need to get an idea of how much it will probably cost them before they commit to working with an orthodontist.

Another thing parents should be aware of is that some practices will have several orthodontists. It is important that a child sees the same dentist every time. Otherwise, there may be no consistent course of treatment.

Parents will want to inquire how an orthodontist deals with children, particularly as regards calming them. Dr. Freedman’s office uses an approach of telling children what the doctor will do, then showing them how it will work, then doing the treatment. Avoiding surprises will make children calmer and more confident about their treatment. Dr. Freedman also recommends using a computer simulation to show a child how the teeth will move around during treatment.

Dr. Freedman notes that orthodontic practice doesn’t involve pain and needles in the office. So a calm, confident doctor will make the children feel better. Patience is a good thing in an orthodontist.

Dr. Freedman’s key suggestion: “Follow your gut.” Parents need to be guided by their good instincts and pick a doctor and an office that make them feel comfortable. If the fee sounds wrong, you may want to look for alternatives.

Matthew Freedman, D.M.D. is an orthodontist practicing with Main Street Children's Dentistry and Orthodontics of Naples, Florida. He attended dental school at Nova Southeastern University. Dr. Freedman started practices in Naples, Bonita Springs, and Ft. Myers. Currently the dental director for the Main Street Children’s Dentistry and Orthodontics group, he still practices full time in Naples, where his son attends the Community School of Naples. Dentist News Network is a featured network of Sequence Media Group.

Does CPAP Prevent Cardiovascular Events in Obstructive Sleep Apnea?

The New England Journal of Medicine recently reported on a study conducted in Australia to determine what effect, if any, CPAP therapy would have on cardiovascular events among sleep apnea patients. The study suggests that CPAP provides no benefits for cardiology patients suffering from sleep apnea. Dr. Lee Surkin, a cardiologist and sleep medicine specialist, discusses the study and what it means in this report.

Dr. Lee Surkin

Dr. Lee Surkin

Dr. Surkin explains that the SAVE (Sleep Apnea Cardiovascular Endpoints) trial studied about 2,700 patients centered around Australia and the Asian continent. The subjects were people with moderate to severe sleep apnea and cardiovascular disease. The stand treatment for sleep apnea is CPAP (continuous positive airway pressure). The study’s aim was to see if CPAP therapy had a positive effect on the cardiovascular system of the sleep apnea patients. About half the patients were on CPAP; the other half were not. The study followed the subjects for about four years. The study’s conclusion was that there was no cardiovascular benefit to adding CPAP to a population of patients with moderate to severe sleep apnea.

The study is important, says Dr. Surkin, because it has long been known in the medical world that, over time, sleep apnea can have an adverse effect on the cardiovascular system. It can “[increase] the risk of heart attack, stroke, heart failure, and heart rhythm disturbances.” What has not been known is whether CPAP therapy for sleep apnea can have a positive impact on cardiovascular problems.

Dr. Surkin notes that there have been studies in the past showing some benefit from the use of CPAP therapy. He points out that the SAVE trial data are from patients who got “a sub-therapeutic dose of CPAP.” The average time that patients in the SAVE trial were on CPAP was 3.3 hours. Considering that a night’s sleep is about seven hours, the patients in this study were only treated for half the night. Even more troublesome is that the CPAP was given during the first half of the subjects’ sleep. Dr. Surkin points out that the second half of the night is when most deep sleep occurs. It is a major concern about the validity of the study that the patients involved were not treated long enough each night.

As to treatment for sleep apnea, guidelines indicate that CPAP should be the first treatment option. And CPAP should be used throughout the night’s sleep. Other treatment options include a dental oral appliance (a mandibular advancement device) created by a board certified dental physician. The device holds the jaw in an advanced position that keeps the airway open during sleep. Another option would be an implanted device that delivers stimulation to nerves in the tongue to keep the tongue forward. There is also Provent, a device placed on the nostrils at bedtime. It develops air pressure that keeps the airway open during sleep. For the long term, sleep apnea patients should work on losing weight.

Dr. Lee Surkin, MD, FACC, FCCP, FASNC is a cardiologist in Greenville, North Carolina and is affiliated with multiple hospitals in the area, including Martin General Hospital and Vidant Medical Center. He received his medical degree from Drexel University College of Medicine and has been in practice for more than 20 years. He is board certified in Cardiology, Nuclear Cardiology and Sleep Medicine. He is the founder of the American Academy of Cardiovascular Sleep Medicine. The Health and Wellness Network is a featured network of Sequence Media Group.

Zika Virus Found In Mosquitos For First Time In US

Marking an official first for the continental United States, authorities in Florida have found the Zika virus in trapped mosquitoes found within a 1.5 square mile area of Miami Beach, according to the LA Times. The find, although not a surprise since dozens of non-travel related cases have popped up in the area this summer, will help mosquito controllers target their efforts now that the insects have been confirmed as the source of transmission. To start their efforts Miami-Dade County’s Mosquito Control team will be conducting inspections to reduce mosquito breeding and will be spraying the eighth of a mile radius around the location where the infected insects were caught.

The US Center for disease control likens the find to a needle in a haystack but are confident in Florida’s capabilities to control the mosquito populations like they have previously done during outbreaks of dengue fever and Chikungunya. Florida Governor Rick Scott has announced according to ABC News that the number of locally transmitted Zika cases have risen to 14.

10 New Zika Virus Cases In Florida Leads To CDC Travel Warning

ABC News is reporting that Florida Governor Rick Scott has activated the emergency response team from the CDC after ten additional cases of the Zika virus were reported in the Miami area. This on the heels of the 4 confirmed cases in the same area last week which were deemed the first time the virus was transmitted via mosquito in the continental United States. Most cases within the United States are still the result of traveling to a country where the virus has an outbreak. The Florida Department of Health confirmed that the ten additional cases were contracted locally, likely by mosquito bites, the department has also tested around 2,300 people for the virus and found 372 infected. 

According to ABC News, six of the ten had no symptoms and were identified through a door to door investigation.

Fears of an outbreak are trying to be calmed by the Governor, who reminded Floridians that the state has a proven track record of success managing mosquito-borne viruses, citing previous outbreaks of dengue fever. Authorities say to drain standing water and wear bug spray.

The CDC has issued a warning that pregnant women should avoid unnecessary travel to the affected areas in Florida.